Acute Respiratory Viral Serology Array

Acute Respiratory Viral Serology Array

The Acute Respiratory Viral Serology (ARVS) Array is a multiplex assay for high-throughput, high-definition serological studies of 27 unique validated recombinant antigens interrogating 3 different viruses.  These viruses and their subtypes include Coronaviruses (SARS-CoV-2, SARS-CoV, MERS-CoV, and 4 common-cold Coronaviruses), Influenza A (H3N2, H1N1, H7N9, H5N1), Influenza B (3 lineages), and Respiratory Syncytial Viruses A and B.  The Coronaviruses have higher definition to interrogate the Spike Receptor Binding Domain (RBD), Spike S1, Spike S1 +S2, and Nucleocapsid proteins (varies by Coronavirus subtype).  SARS-CoV-2 also includes the mutant D614G protein.  The array is designed to determine the antibody profile in serum samples with applications in epidemiology and serosurveillance, vaccine development, and basic translational research.
  • Available as complete respiratory viral serology array and as a COVID-19 focus Array
  • Utilizes Adarza’s AIR technology for high sensitivity and multiplex

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Specifications:

Analytes:

Influenza A Wisconsin H3N2
Influenza A Texas H3N2
Influenza A California H1N1
Influenza A Beijing H1N1
Influenza A Shanghai H7N9
Influenza A Vietnam H5N1
Influenza B Massachusetts
Influenza B Phuket
Influenza B Malaysia
CoV-HKU1 S1
CoV-229E S1 + S2
CoV-OC43 S1+ S2
CoV-NL63 S1
SARS-CoV-2 mutant D614G
SARS-CoV-2 S1
SARS-CoV-2 RBD
SARS-CoV-2 Nucleocapsid
SARS-CoV-2 S1 + S2
SARS-CoV-2 S2
MERS-CoV S1
MERS-CoV RBD
MERS-CoV Nucleocapsid
SARS-CoV S1
SARS-CoV RBD
SARS-CoV Nucleocapsid
RSV A G Protein
RSV B G Protein

Kit Contents

Reagent Volume Quantity Storage
96 well consumable with biosensor array N/A 1 4˚C
Clear Plate Seal 1 1 RT
Plate Lid 1 1 RT
Negative Control 100µl 1 4°C
Positive Control* 25µl 1 4°C
Assay Buffer 16ml 1 4˚C
ZIVA™ Wash Buffer (ZWB) 50ml of 20X 1 4˚C
*The positive control contains a mixture of antibodies that result in a positive response to the following antigens: SARS-CoV-2 RBD, SARs-CoV-2 S1, SARS-CoV-2 D614G, SARS-CoV RBD, MERS-CoV RBD, Influenza B Malaysia, Influenza B Phuket

Resources & Data

Documentation

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